Anti-Müllerian hormone (AMH) is a dimeric glycoprotein that belongs to the beta-transforming growth factor family. In males, AMH is secreted by Sertoli cells and is responsible for the regression of the Müllerian ducts during embryonic development. The secretion of the hormone begins at 7-8 weeks of fetal development and continues until postpuberty, gradually decreasing.

In women, AMH is produced by granulosa cells of ovarian follicles and is an important indicator of ovarian reserve. The level of AMH in women is positively correlated with the number of antral follicles and also changes with age. With age, after puberty, AMH levels decrease, which is a sensitive predictor of menopause.

Indications for prescription:

In women:

• Diagnosis of the causes of ovulatory dysfunction, subfertility and infertility
• Diagnosis and monitoring of the effectiveness of PCOS (polycystic ovary syndrome) treatment
• Diagnosis and monitoring of the effectiveness of granulosa cell ovarian cancer treatment
• Diagnosis of premature ovarian failure (primary and iatrogenic)

In men:

• Evaluation of male sexual function and diagnosis of infertility causes
• Diagnosis of the persistent mullerian duct syndrome
• Monitoring the effectiveness of antiandrogen therapy

In children and adolescents:

• Detection of premature sexual development or delayed sexual development
• Differential diagnosis of cryptorchidism and anorchidism
• Differential diagnosis of intersex conditions
• Biological material: venous blood (serum tube)

Patient preparation rules:

• 4 hours before the collection: refrain from eating, exclude fatty foods
• You can drink water
• For children under 1 year of age: it is advisable to donate blood before feeding or with the longest possible pause between feedings

Important:

• Depending on the diagnostic tasks, the optimal time of day for taking biological material is determined by the doctor.
• For women, depending on the diagnostic tasks, the optimal days of the menstrual cycle are determined by the doctor.

Contraindications: none

Time frame: 24 hours