Prolactin is a peptide hormone secreted by the lactotrophs of the anterior pituitary gland, as well as in smaller amounts by the decidual membrane and endometrium.

The main role of prolactin is to regulate the growth and development of the mammary glands, as well as to ensure lactation.

In women:

• Normal levels of prolactin contribute to the synthesis of progesterone by the corpus luteum.
• Excessive production of the hormone can inhibit the secretion of gonadotropins, disrupting ovulation, which is the cause of infertility, cycle disorders, and luteal phase insufficiency.

In men:

• Normally, prolactin supports testosterone production.
• In case of hyperprolactinemia, it can reduce testosterone levels, cause a decrease in libido, potency, and gynecomastia.
• Prolactin is also a stress hormone, its level can increase due to emotional or physical overload, changes in time zones, and exposure to unfavorable environmental factors.

Features of secretion:

• It has a daily (circadian) rhythm: higher in the morning, lower in the evening.
• Higher in the luteal phase of the menstrual cycle than in the follicular phase.
• The level increases during puberty, decreases during menopause.

Indications for the analysis:

• Menstrual irregularities
• Anovulation, luteal insufficiency, infertility
• Galactorrhea (milk production outside the lactation period)
• Benign breast diseases
• Lactation disorders
• Symptoms of hyperandrogenism
• Decreased libido and potency in men
• Gynecomastia
• Monitoring of drug treatment

Preparation for the test:

• 4 hours before the test - do not eat, avoid fatty foods
• You can drink water
• For children under 1 year old - it is advisable to maintain the maximum interval between feedings or take the test before feeding
• The time of blood sampling and the day of the cycle for women is determined by the doctor depending on the diagnostic tasks

Material for the test: venous blood

Contraindications: none

Time frame: 24 hours