Total protein

The study of the level of blood serum protein is prescribed very often, it is included in the standard program for diagnosing such diseases:

• malnutrition and diseases of the digestive tract;
• pathology of the hepatobiliary system;
• acute and chronic kidney disease;
• metabolic disorders in endocrine diseases;
• infectious diseases;
• malignant neoplasms;
• systemic connective tissue diseases;
• anemia, hemolysis of erythrocytes, and other pathologies of the blood system.

Analysis for total protein as part of blood biochemistry is prescribed for pregnant women, patients who are examined for infertility or are preparing for assisted reproductive technologies. The study is also carried out as part of routine medical examinations and health check-ups to check the state of metabolism in the body.

If the doctor needs to assess the state of protein metabolism in detail, he will prescribe a proteinogram - a study of all protein fractions of blood serum, the results of which help in making an accurate diagnosis.

Before taking a blood test for protein, you must follow these rules:

• do not smoke for 30 minutes before the study;
• 10-12 hours before visiting the manipulation room, refuse to eat;
• in the morning on the day of the study, do not drink coffee, tea, fruit juices, and if you are very thirsty, drink some non-carbonated mineral water;
• the day before the diagnosis, avoid strong emotional upheavals and heavy physical exertion;
• 2 days before the test, give up alcohol.

Taking medications can affect the level of blood protein, therefore, in agreement with the doctor, drug therapy is temporarily canceled before the study.

Diagnostics is carried out by generally accepted standards of medical services in Ukraine. For analysis, you need to obtain a sample of venous blood. The procedure is performed in a manipulation room: a tourniquet is put on the patient’s hand, they are asked to make a fist several times, after which the nurse punctures the vein and fills the test tube with blood.

The biomaterial is sent to the laboratory to analyze the protein level using a special device. Automated research eliminates the human factor and allows you to get accurate results of the protein level.

The form will indicate the protein content in grams per liter, as well as the reference value of this indicator for a particular laboratory. In the blood of an adult healthy person, 65-85 g / l of total protein is determined, however, there are physiological reasons for small deviations from the norm. You should not try to independently evaluate the results: only a doctor can correctly interpret the data and suggest a diagnosis.

A decrease in protein to 55-65 g / l is typical for pregnant women, especially in the third trimester. A pathological decrease in the amount of protein occurs with prolonged food restrictions, diseases of the kidneys, liver, and cardiovascular system, and malabsorption of nutrients in the intestine. An increased indicator in the study of the level of total blood protein may indicate autoimmune diseases, acute infectious processes, dehydration, intoxication syndrome.

Both a decrease and an increase in the level of total protein in the blood are signs of health problems. In such a situation, one should not delay contacting a doctor and undergoing an additional examination.

In the clinic MC "Dobrobut" you can analyze total blood protein at an affordable price. If necessary, there is an urgent examination service with results obtained in a few hours, but its cost will be higher. All tests in our clinic are performed by appointment without waiting in line.

You can sign up for a study of total protein in Kyiv by phone or by filling out an application in the feedback form.

1. Плахотник, Ю. Ю. Вплив фізичного навантаження на показники загального білку сироватки крові у жінок другого періоду зрілого віку. (2020).
2. Hogan, Jonathan J., Mariam Priya Alexander, and Nelson Leung. Dysproteinemia and the kidney: core curriculum 2019. American Journal of Kidney Diseases 74.6 (2019): 822-836.
3. Zheng, Kangle, et al. Measurement of the total protein in serum by biuret method with uncertainty evaluation. Measurement 112 (2017): 16-21.
4. Hunsaker JJH, Wyness SP, Snow TM, Genzen JR. Clinical performance evaluation of total protein measurement by digital refractometry and characterization of non-protein solute interferences. Pract Lab Med. 2016;6:14-24. Published 2016 Aug 17.