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Determination of the level of prolactin (PRL)
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Determination of the level of prolactin (PRL)

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Prolactin (PRL) is a hormone secreted by the pituitary gland. It is very important for a person, as it is responsible for the overall development of the body, controls the metabolic rate and growth processes in both women and men.

In the clinic MC "Dobrobut" in Ukraine, you can quickly and painlessly determine the level of prolactin in the blood at the best prices in Kyiv. Our laboratory and diagnostic base allow you to get extremely accurate results the very next day after the analysis.

Why do you need to take a PRL analysis

Of particular importance is the level of PRL for pregnant women, since during the period of gestation and after the birth of a child, prolactin provides sufficient lactation, that is, the formation, accumulation, and secretion of breast milk by the mammary glands.

An analysis of prolactin is important for women who are just planning a pregnancy since the level of the hormone in the blood affects reproductive function, that is, the ability to conceive. So, an excess indicator sharply reduces fertility - a woman's ability to reproduce healthy offspring, as it causes a violation of the process of egg maturation.

When is an examination scheduled?

A blood test for prolactin is prescribed by a doctor. One of the most common reasons for the diagnosis is a discharge from the mammary glands that are not associated with feeding the child. Such a deviation can be observed in women who have never become pregnant, men, and even children.

Other reasons may be:
  • Violation of the periodicity and duration of the menstrual cycle.
  • Delayed periods for 6 months or more in the absence of pregnancy and signs of menopause.
  • Profuse discharge during menstruation.
  • Lack of maturation of the egg.
  • Severe menopause.
  • Inability to achieve pregnancy within 12 months of active sexual life without the use of contraception.
  • Violation of the production of breast milk during the period of feeding the child.
  • Decreased sexual desire in both men and women of active age.
  • Decreased potency.

How is the PRL analysis performed?

The level of the hormone can change under the influence of various circumstances. Therefore, it is necessary to prepare for the analysis of prolactin and follow all the recommendations of the doctor to obtain accurate results.

It will take 2-3 days to prepare. It consists of the following:

  • It is necessary to exclude hard work, active sports, protect yourself from stressful situations.
  • It is necessary to refuse to visit the sauna, bath, solarium.
  • It is important to refrain from intimacy.
  • It is necessary to exclude alcohol, heavy and fatty foods from the diet.

The prolactin test is usually scheduled for the morning. The interval between the last meal and the visit to the laboratory should be at least 8 hours. It is better to arrive 30-40 minutes before the appointed time, as doctors recommend being completely at rest for 25-35 minutes before the analysis.

Women should first consult a doctor to choose the most suitable day for sampling. This is because the phase of the menstrual cycle affects the result.

For the study, venous blood is needed. It is taken from the cubital vein by the puncture.

The results of the analysis for the hormone prolactin

It should be noted right away that only a doctor can make the correct decoding of the analysis. The average (reference) value of the indicator will be as follows:

When deciphering the analysis in women, the phase of the menstrual cycle is taken into account:

  1. Follicular - 136-999 μIU / ml.
  2. Ovular - 190-1484 μIU / ml.
  3. Luteal - 148-1212 μIU / ml.

During pregnancy, the level of the hormone will constantly increase and reach a peak value in the last trimester.

How to make an appointment for prolactin (PRL) test

You can sign up for laboratory tests at our Dobrobut MC clinic by phone or by filling out an application form on our website. Our manager will call you back within a few minutes and sign you up for a convenient day. We draw your attention to the fact that you need to take prolactin in the morning on an empty stomach.

You can find out the cost of a blood test for prolactin from the manager of the clinic or on our website. The price includes all consumables.

Sign up to our clinic MC "Dobrobut" in Kyiv and undergo an examination in a comfortable environment without queues. Our laboratory is equipped with equipment from the best world manufacturers, so we guarantee a reliable result.

In case of deviation of the indicators from the norm, you can get a consultation from the doctor of our clinic. It will help to adjust the level of the hormone by prescribing drug therapy and correcting eating behavior.

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Bibliography

  1. Al-Chalabi M, Bass AN, Alsalman I. Physiology, Prolactin. [Updated 2021 Jul 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan.
  2. Пирогова, В. І. Клінічні аспекти синдрому гіперпролактинемії. (2019).
  3. Saleem M, Martin H, Coates P. Prolactin Biology and Laboratory Measurement: An Update on Physiology and Current Analytical Issues. Clin Biochem Rev. 2018;39(1):3-16.
  4. Hu Y, Ding Y, Yang M, Xiang Z. Serum prolactin levels across pregnancy and the establishment of reference intervals. Clin Chem Lab Med. 2018 Apr 25;56(5):838-842.
  5. Кузьміна, Ольга Олександрівна, Надія Асхатівна Сафаргаліна-Корнілова, and Ірина Юріївна Кузьміна. Вибір методу терапії жінок з ендокринним безпліддям та гіперпролактинемією. Diss. 2017.

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